Western diets and lifestyles are instrincally pro-inflammatory because of high carbohydrate diets, micronutrient deficiencies, toxic stress, sleep deprivation, lack of sunshine, exposure to microbes (high population and travel) and vaccination. What helps to mitigate these effects is good antioxidant status - this helps to quench the pro-inflammatory "fire".
Eating a stone-age diet, sleeping well, taking the "Basic Package" of micronutrient supplements and avoiding toxic stress and infections go a long way to mitigate the problems of Westerners. However, many benefit from taking additional antioxidants - this is to be expected where tests show deficiencies. Detailed information about this group of nutrients can be found at Antioxidants.