PACKAGE - MITOCHONDRIAL PACKAGE (Starter Kit): 5 items
1x Niacinamide B3
1x B12 Methylcobalamin
Dr Myhill also recommends Epsom Salts - this can be purchased online from http://www.justasoap.co.uk/epsom-salt.html
Please note this is a starter kit and some products will last longer than others. If you require additional items please order in the normal fashion from the A-Z list. (For CFS patients add in VegEPA 2-4 capsules daily).
This package can be taken in conjunction with the Basic package.
Acetyl-L-Carnitine is the fuel pipe which delivers the fuel (acetate groups) into the engines (mitochondria). Levels are often low in CFSs, especially when they are vegetarian (the word carnitine derives from carnivore).
One scoop of Acetyl-L-Carnitine contains one gram. A typical daily dose would be 1-2 grams.
Although the product does not contain Gluten we do not label the product as 'Gluten Free' as we would need to guarantee the product has been kept away from Gluten at every stage of the supply chain or test the batch for Gluten content. We would expect the product to be tolerated by coeliacs.
The energy molecule ATP is recycled between mitochondria and cells with incredible efficiency. However, if mitochondrial function is impaired, as in CFS, then the leakage of ATP is much higher. For a full explanation see CFS_-_The_Central_Cause:_Mitochondrial_Failure
Cells have then to make brand new ATP. But this is a difficult bit of biochemistry involving many raw materials and a tricky piece of biochemistry called the pentose phosphate shunt - it takes hours, possibly days, to restore normal ATP and this may explain the delayed fatigue and post-exertional malaise in CFS.
D-Ribose allows the cells to skip the difficult bits and feed this five carbon sugar directly into ATP synthesis.
The commonest problem with D-Ribose occurs where there is fermenting gut because it has the potential to be fermented. In this event it should be saved for occasional use as a rescue remedy. It is absolutely fine and safe to take D-Ribose long term so long as you are in ketosis.
Otherwise a reasonable dose would be 5-15grams daily.
Although the product does not contain Gluten we do not label the product as 'Gluten Free' as we would need to guarantee the product has been kept away from Gluten at every stage of the supply chain or test the batch for Gluten content. We would expect the product to be tolerated by coeliacs. Suitable for Vegans.Niacinamide:
ONE TABLET CONTAINS 1500mg Niacinamide.
Other ingredients : stearic acid, modified cellulose gum and magnesium stearate. Suitable for vegetarians & hypoallergenic.
Niacinamide or vitamin B3 is essential to make nicotinamide adenine dinucleotide (NAD) – the intermediary between Kreb's citric acid cycle and oxidative phosphorylation. It is, therefore, essential for energy production. So any condition requiring energy may benefit from high dose B3. It is of proven benefit in chronic fatigue syndrome, diabetes, in many mental disorders with psychosis (see the work of Dr Abram Hoffer), arthritis (see the work of Dr William Kaufman) and some degenerative neurological diseases such as Alzheimer’s.
It appears to work by improving energy delivery so that the business of healing and repair can be powered. This squares with the observations of Dr William Kaufman, who in 1949 showed that niacinamide was an effective treatment almost regardless of the cause of the arthritic damage.
Dose 1500 to 3000 mgs daily. Some authorities suggest that niacinamide in high doses may be toxic. Any such risk would be greatly mitigated by eating stoneage diet and taking the Basic Package of supplements.
NOTE : If you are pregnant, may become pregnant or breastfeeding consult your healthcare professional before using this product.
Co-enzyme Q 10 is the most important donator and acceptor of electrons in oxidative phosphorylation. Think of it as the oil which allows the engine to run smoothly. In theory the body should be able to synthesise all it needs, but where there are micronutrient deficiencies or fermenting gut, then deficiency is to be expected. It is unusual to see normal blood levels of Co Q 10 in CFSs who are not supplementing.
Oral Ubiquinol may offer improved bio-availability in individuals who have difficulty achieving high levels of this nutrient, such as ageing adults or those concerned with nutrient absorption.
Suggested dose - Take 1 softgel daily with food or as recommended by your healthcare professional.
Nutritional Information: Each capsules typically provides Keneka Ubiquinol) reduced form of CoQ10.
Other ingredients : Bulking agent (repeseed Oil), Ubiquinol (Kaneka Ubiquinol), Emulsifier (Diglyceryl monooleste), Modified Starch (Corn), Vegetable Glycerol, Thickenre (Beeswax) Carrageenan, Emulsifier (Soya Lecithin), Colour (Caramel), Disodium Phosphate.
FREE FROM: Gluten, Salt, Sugar, Sweetners, Artificial Colours, Artificial Flavours, Artificial Preservatives.
Biologically Active Form of B12
Support for Nerve Function, Energy Production & Red Blood Cells
Purity & Potency Guaranteed
Methylcobalamin is active immediately upon absorption, while other forms (e.g., cyanocobalamin) must be converted to methylcobalamin in a two-step process. Methylcobalamin demonstrates exceptional activity in areas where other forms are simply not active. B12 supplementation is recommended for vegetarians and those suffering from B12 deficiency.
Take one per day with water.
Ingredients: Bulking agents (Dicalcium Phosphate, Microcrystalline Cellulose) Anti-caking Agents (Silicon Dioxide, Stearic Acid), Glazing Agents (HydroPropylMethylCellulose, Glycerin, Camauba Wax), Vitamin B12 (Methylcobalamin).
FREE FROM: Celery, Celeriac, Gluten, Crustaceans, Egg, Fish, Lupin, Diary, Mollusc, Nuts, Nut derived oils, Peanut, Mustard, Sesame seed, Soya.
CAUTION: Food supplements should not be used as a substitute for a varied diet. Do not exceed the stated intake. Excessive consumption may produce laxative effects. Always consult your GP before taking food supplements. Discontinue use and consult a doctor if adverse reactions occur.